Dermaheal USA Corp.

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Science:

The scientific foundation of Dermaheal is based on the understanding of cellular and molecular biology of the aging or damaged cell. There are intricate networks of proteins which are involved in cellular turnover and longevity. The active ingredients that are incorporated in Dermaheal products were discovered based on this scientific knowledge. They are patented molecules which mimic the functions of cellular proteins, therefore, are the most effective in their ability to intervene in cellular processes, such as aging and pigmentation.

A group of proteins that are used in Dermaheal products are called growth factors. Throughout decades of extensive basic research, the importance of growth factors in cellular turnover, metabolism, and immunity has been demonstrated. Growth factors are naturally occurring molecules that are produced by our body. Normal cell division and differentiation (and therefore regeneration) are dependent on these growth factors. Growth factors help proliferation of fibroblasts in epidermis and keratinocytes in dermis, therefore stimulating the production of extra cellular matrix proteins such as hyaluranic acid, collagen, and elastin. This, in turn, will help the damaged or aged skin tissue to regenerate itself, which will result in reducing wrinkles and increasing the skin’s elasticity.

Another group of potent ingredients used in Dermaheal are small molecules or peptides which have similar functions to those of growth factors. Most of them engage the same receptor complex as their corresponding growth factors. They are patented molecules with high potency which target the skin cells to stimulate their regeneration. Some of them have anti-aging effects and some act as anti-pigmentation agents.



What is the benefit of growth factor-mimicking peptides in anti-aging?

As we age, the ability of our skin’s cells to regenerate themselves decreases. What occurs next shows that the cellular turnover pace slows down to about 50% of its original rate, which in turn, has revealed that these are clear signs of the skin aging. Dermaheal, with its growth factor mimicking peptides, stimulates aged skin cells to revert to a more youthful state by stimulating the cellular turnover and improving the overall quality of the skin. The overwhelming success of growth factor mimicking peptides is due to the fact that unlike other anti-aging ingredients, they cause no irritation because they are 100% bio-identical to the body’s natural proteins. They are immediately absorbed by the skin cells and utilized by the cellular machinery for protein synthesis and cellular regeneration.



The effect of Dermaheal anti-aging peptides on cell cultures and skin tissue



What is the active ingredient in the Dermaheal anti-pigmentation products?

Skin pigmentation is a major problem with few effective treatments available to customers in the market. Skin pigmentation is usually manifests itself as dark spots or sun spots, which is due to the production of melanin in the skin’s cells. An effective therapy could stop the production of this molecule. Unlike some leading brands, which use toxic bleaching agents such as hydroquinone, Dermaheal utilizes a patented novel peptide which acts specifically on melanin synthesis without damaging neighboring cells. This approach is gentle, yet extremely effective in removing pigmentation and age spots.



The molecular mechanism of pigmentation is depicted in this picture. The Dermaheal patented peptideTGP2 specifically acts on melanin synthesis without damaging the cell.




The effect of Dermaheal anti-pigmentation peptide in melanin synthesis